Monday, June 23, 2025

Antidote 3 Rattler Antivenin

 


Antidote 3 Rattler Antivenin

ANTIDOTE 3 Rattler Antivenin is a veterinary product used to treat envenomation (snakebite) in canine, equine, and feline patients. It is a polyvalent antivenin of equine origin, meaning it contains antibodies derived from horses that have been immunized against the venoms of various North American pit vipers, including:
 
  • Rattlesnakes: Western Diamondback, Eastern Diamondback, Prairie Rattlesnake, and Mohave Rattlesnake Type A. Tildren 5mg/ml
  • Copperheads.
  • Cottonmouths/Water Moccasins.
 

Key Information about ANTIDOTE 3 Rattler Antivenin:

  • Mechanism of Action: Contains antibodies that neutralize venom, decreasing swelling, minimizing pain, and decreasing temperature.
  • Administration: Administered intravenously using a filtered IV set.
    • Feline: 2-3 mL/kg/hour.
    • Canine and Equine: Over a 20-60 minute period.
  • Dosage: One to two 50ml doses are typically sufficient, but additional doses may be needed depending on the severity of the envenomation, type/size of snake, and patient size.
  • Efficacy: Demonstrated high survival rates in clinical trials for treated canine (93%) and equine (100%) patients. It effectively neutralizes venom and reduces the severity of envenomation symptoms.
  • Safety: Considered safe for use in affected species. Hypersensitivity reactions are rare but possible.
  • Note: It is crucial to administer the product as is, without reconstitution or dilution.
  • FDA Approval: Rattler Antivenom has obtained USDA licensure, indicating it has met stringent requirements for safety and efficacy.
  • Cost: The cost can vary depending on the supplier. 

 

Important Considerations:

  • Consult a veterinarian: ANTIDOTE 3 Rattler Antivenin is restricted to use by or under the direction of a licensed veterinarian.
  • Timing of administration: For best results, antivenin should be administered as soon as possible after a snakebite.
  • Monitoring for adverse reactions: Patients should be monitored for signs of anaphylaxis or other adverse events during and after administration

Usage of Antidote 3 Rattler Antivenin

Use of Rattler Antivenom within 24 hours of snakebite neutralizes venom, decreases swelling, minimizes pain, and decreases temperature of canine, equine, and feline patients. Rattler Antivenom neutralizes venom from rattlesnakes, copperheads, and cottonmouths/watermoccasins.-year shelf life. Stored frozen, Rattler Antivenom is good for three years from manufacture date.

Three-Year Shelf Life. Stored frozen, Rattler Antivenom is good for three years from manufacture date.

Ready to Use in Five Minutes. Thaw using a warm water bath; does NOT require reconstitution or dilution.

North American Venoms. Rattler Antivenom is formulated using N. American Venoms (Western Diamondback Rattlesnake, Eastern Diamondback Rattlesnake, Prairie Rattlesnake, and Mohave Rattlesnake Type A).

Cross-protective. Shown to be effective against envenomation in canine, equine, and feline due to North American Crotalidae. Crotalidae refers to the Crotalinae subfamily (commonly named ‘Pit Vipers’) and includes rattlesnakes, copperheads, and cottonmouths/water moccasins.

Neutralizes Venom. Packaged in a “One-and-Done” IV pouch. Combining research from both in the field and in the lab, Rattler Antivenom is potent enough to treat the typical envenomation case with a single dose.

Neutralizes Mohave Venom A. The only licensed product that includes specific antibodies proven to neutralize venom from Mohave Rattlesnake Type A.

Safe to Use. May be used alongside typical post-snake bite therapies. Safe with Vaccine. Safe and compatible for use in previously vaccinated patients. Rattler Antivenom shares no common proteins with the industry’s most widely used rattlesnake vaccine.

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